AEROPATH Target Database

Target Listing

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Page 1 of 3, showing 25 records out of 56 total, starting on record 1, ending on 25
Locus tag Gene name Product name ChEMBL homologs Chemogenomic druggability rank Mean QED Structure-based druggability Essentiality Virulence Factor Drug Target Human homologs Microbes havings orthologs Structures solved Structural homologs XtalPred Class
PA0408 pilG twitching motility protein PilG 5 470 0.68 - E YES - 0 2/4 0 282 1
PA0409 pilH twitching motility protein PilH 5 353 0.68 - N YES - 0 2/4 0 309 1
PA0413 chpA component of chemotactic signal trans... 6 355 0.68 - N YES - 0 2/4 0 357 5
PA0555 fda fructose-1,6-bisphosphate aldolase 6 560 0.17 - E - - 0 3/4 0 71 2
PA0576 rpoD sigma factor RpoD 1 147 0.06 - E - - 0 4/4 0 51 5
PA0672 hemO heme oxygenase 1 7 0.54 - E - - 0 2/4 0 5 3
PA1456 cheY two-component response regulator CheY 5 329 0.68 - E - - 0 2/4 0 269 1
PA1681 aroC chorismate synthase 1 378 0.52 - E - - 0 4/4 0 27 2
PA1816 dnaQ DNA polymerase III, epsilon chain 3 520 0.54 - E - - 0 4/4 0 8 5
PA2977 murB UDP-N-acetylpyruvoylglucosamine reduc... 2 359 0.28 - E - - 0 4/4 0 10 2
PA2943 - phospho-2-dehydro-3-deoxyheptonate al... 3 260 0.13 - P - - 0 1/4 0 71 3
PA2586 gacA response regulator GacA 4 752 0.25 - N YES - 0 4/4 0 104 3
PA2276 - probable transcriptional regulator 1 954 0.21 - E - - 0 2/4 0 0 4
PA2192 - conserved hypothetical protein 1 904 0.22 - E - - 0 0/4 0 31 1
PA2191 exoY adenylate cyclase ExoY 1 614 0.57 - N YES - 0 0/4 0 65 3
PA1903 phzE2 phenazine biosynthesis protein PhzE 2 348 0.75 - N YES - 0 0/4 0 46 4
PA1882 - probable transporter 2 99 0.54 - E - - 0 2/4 0 16 5
PA1713 exsA transcriptional regulator ExsA 1 5 0.21 - E YES - 0 1/4 0 1 4
PA4450 murA UDP-N-acetylglucosamine 1-carboxyviny... 3 21 0.34 - P - YES 0 4/4 0 73 1
PA4417 murE UDP-N-acetylmuramoylalanyl-D-glutamat... 6 525 0.58 - E - - 0 4/4 0 16 2
PA4416 murF UDP-N-acetylmuramoylalanyl-D-glutamyl... 6 543 0.58 - E - - 0 4/4 0 7 1
PA4415 mraY phospho-N-acetylmuramoyl-pentapeptide... 4 137 0.20 - E - - 0 4/4 0 0 5
PA4414 murD UDP-N-acetylmuramoylalanine--D-glutam... 6 931 0.43 - P - - 0 4/4 0 22 1
PA4411 murC UDP-N-acetylmuramate--alanine ligase 7 932 0.43 - E - - 0 4/4 0 42 5
PA4231 pchA salicylate biosynthesis isochorismate... 2 417 0.75 - N YES - 0 4/4 0 40 2
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