AEROPATH Target Database

Target Listing

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Page 1 of 3, showing 25 records out of 56 total, starting on record 1, ending on 25
Locus tag Gene name Product name ChEMBL homologs Chemogenomic druggability rank Mean QED Structure-based druggability Essentiality Virulence Factor Drug Target Human homologs Microbes havings orthologs Structures solved Structural homologs XtalPred Class
PA2276 - probable transcriptional regulator 1 954 0.21 - E - - 0 2/4 0 0 4
PA3145 wbpL glycosyltransferase WbpL 4 674 0.20 - N YES - 0 1/4 0 0 5
PA4415 mraY phospho-N-acetylmuramoyl-pentapeptide... 4 137 0.20 - E - - 0 4/4 0 0 5
PA1713 exsA transcriptional regulator ExsA 1 5 0.21 - E YES - 0 1/4 0 1 4
PA0672 hemO heme oxygenase 1 7 0.54 - E - - 0 2/4 0 5 3
PA1619 - probable transcriptional regulator 1 661 0.21 - E - - 0 2/4 0 7 5
PA4416 murF UDP-N-acetylmuramoylalanyl-D-glutamyl... 6 543 0.58 - E - - 0 4/4 0 7 1
PA1816 dnaQ DNA polymerase III, epsilon chain 3 520 0.54 - E - - 0 4/4 0 8 5
PA3640 dnaE DNA polymerase III, alpha chain 4 406 0.49 - E - - 0 4/4 0 9 5
PA2977 murB UDP-N-acetylpyruvoylglucosamine reduc... 2 359 0.28 - E - - 0 4/4 0 10 2
PA1882 - probable transporter 2 99 0.54 - E - - 0 2/4 0 16 5
PA4417 murE UDP-N-acetylmuramoylalanyl-D-glutamat... 6 525 0.58 - E - - 0 4/4 0 16 2
PA1098 fleS two-component sensor 5 866 0.54 - N YES - 0 0/4 0 17 4
PA4119 aph aminoglycoside 3'-phosphotransferase ... 1 22 0.21 - E - - 0 1/4 0 17 4
PA4546 pilS two-component sensor PilS 5 573 0.46 - N YES - 0 2/4 0 18 5
PA3528 rnt ribonuclease T 2 705 0.54 - E - - 0 4/4 2 22 3
PA4414 murD UDP-N-acetylmuramoylalanine--D-glutam... 6 931 0.43 - P - - 0 4/4 0 22 1
PA4457 - arabinose-5-phosphate isomerase KdsD 2 238 0.22 - E - - 0 4/4 0 22 1
PA1681 aroC chorismate synthase 1 378 0.52 - E - - 0 4/4 0 27 2
PA1455 fliA sigma factor FliA 1 960 0.06 - N YES - 0 2/4 0 31 2
PA2192 - conserved hypothetical protein 1 904 0.22 - E - - 0 0/4 0 31 1
PA1430 lasR transcriptional regulator LasR 4 8 0.68 mixed N YES - 0 0/4 23 32 2
PA4406 lpxC UDP-3-O-acyl-N-acetylglucosamine deac... 3 1 0.54 druggable E - - 0 4/4 4 32 1
PA4231 pchA salicylate biosynthesis isochorismate... 2 417 0.75 - N YES - 0 4/4 0 40 2
PA3477 rhlR transcriptional regulator RhlR 5 300 0.68 - N YES - 0 2/4 0 41 4
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