AEROPATH Target Database

Target Listing

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Page 1 of 3, showing 25 records out of 56 total, starting on record 1, ending on 25
Locus tag Gene name Product name ChEMBL homologs Chemogenomic druggability rank Mean QED Structure-based druggability Essentiality Virulence Factor Drug Target Human homologs Microbes havings orthologs Structures solved Structural homologs XtalPred Class
PA1098 fleS two-component sensor 5 866 0.54 - N YES - 0 0/4 0 17 4
PA1099 fleR two-component response regulator 5 379 0.68 - N YES - 0 0/4 0 311 4
PA1430 lasR transcriptional regulator LasR 4 8 0.68 mixed N YES - 0 0/4 23 32 2
PA2192 - conserved hypothetical protein 1 904 0.22 - E - - 0 0/4 0 31 1
PA3724 lasB elastase LasB 2 4 0.35 ambiguous N YES - 0 0/4 3 108 4
PA4214 phzE1 phenazine biosynthesis protein PhzE 2 349 0.75 - N YES - 0 0/4 0 46 4
PA3156 wbpD UDP-2-acetamido-3-amino-2,3-dideoxy-d... 1 519 0.55 - N YES - 0 0/4 0 98 3
PA2191 exoY adenylate cyclase ExoY 1 614 0.57 - N YES - 0 0/4 0 65 3
PA1903 phzE2 phenazine biosynthesis protein PhzE 2 348 0.75 - N YES - 0 0/4 0 46 4
PA1713 exsA transcriptional regulator ExsA 1 5 0.21 - E YES - 0 1/4 0 1 4
PA3145 wbpL glycosyltransferase WbpL 4 674 0.20 - N YES - 0 1/4 0 0 5
PA4119 aph aminoglycoside 3'-phosphotransferase ... 1 22 0.21 - E - - 0 1/4 0 17 4
PA2943 - phospho-2-dehydro-3-deoxyheptonate al... 3 260 0.13 - P - - 0 1/4 0 71 3
PA0408 pilG twitching motility protein PilG 5 470 0.68 - E YES - 0 2/4 0 282 1
PA0409 pilH twitching motility protein PilH 5 353 0.68 - N YES - 0 2/4 0 309 1
PA0413 chpA component of chemotactic signal trans... 6 355 0.68 - N YES - 0 2/4 0 357 5
PA1456 cheY two-component response regulator CheY 5 329 0.68 - E - - 0 2/4 0 269 1
PA1619 - probable transcriptional regulator 1 661 0.21 - E - - 0 2/4 0 7 5
PA4546 pilS two-component sensor PilS 5 573 0.46 - N YES - 0 2/4 0 18 5
PA3477 rhlR transcriptional regulator RhlR 5 300 0.68 - N YES - 0 2/4 0 41 4
PA2276 - probable transcriptional regulator 1 954 0.21 - E - - 0 2/4 0 0 4
PA1882 - probable transporter 2 99 0.54 - E - - 0 2/4 0 16 5
PA1455 fliA sigma factor FliA 1 960 0.06 - N YES - 0 2/4 0 31 2
PA0672 hemO heme oxygenase 1 7 0.54 - E - - 0 2/4 0 5 3
PA0555 fda fructose-1,6-bisphosphate aldolase 6 560 0.17 - E - - 0 3/4 0 71 2
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