AEROPATH Target Database

Target Listing

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Page 1 of 3, showing 25 records out of 56 total, starting on record 1, ending on 25
Locus tag Gene name Product name ChEMBL homologs Chemogenomic druggability rank Mean QED Structure-based druggability Essentiality Virulence Factor Drug Target Human homologs Microbes havings orthologs Structures solved Structural homologs XtalPred Class
PA0576 rpoD sigma factor RpoD 1 147 0.06 - E - - 0 4/4 0 51 5
PA1455 fliA sigma factor FliA 1 960 0.06 - N YES - 0 2/4 0 31 2
PA2943 - phospho-2-dehydro-3-deoxyheptonate al... 3 260 0.13 - P - - 0 1/4 0 71 3
PA0555 fda fructose-1,6-bisphosphate aldolase 6 560 0.17 - E - - 0 3/4 0 71 2
PA3145 wbpL glycosyltransferase WbpL 4 674 0.20 - N YES - 0 1/4 0 0 5
PA4415 mraY phospho-N-acetylmuramoyl-pentapeptide... 4 137 0.20 - E - - 0 4/4 0 0 5
PA1619 - probable transcriptional regulator 1 661 0.21 - E - - 0 2/4 0 7 5
PA1713 exsA transcriptional regulator ExsA 1 5 0.21 - E YES - 0 1/4 0 1 4
PA4119 aph aminoglycoside 3'-phosphotransferase ... 1 22 0.21 - E - - 0 1/4 0 17 4
PA2276 - probable transcriptional regulator 1 954 0.21 - E - - 0 2/4 0 0 4
PA2192 - conserved hypothetical protein 1 904 0.22 - E - - 0 0/4 0 31 1
PA4457 - arabinose-5-phosphate isomerase KdsD 2 238 0.22 - E - - 0 4/4 0 22 1
PA2586 gacA response regulator GacA 4 752 0.25 - N YES - 0 4/4 0 104 3
PA4776 pmrA PmrA: two-component regulator system ... 2 642 0.25 - E - - 0 3/4 0 278 1
PA4931 dnaB replicative DNA helicase 4 9 0.27 - E - - 0 4/4 0 44 4
PA2977 murB UDP-N-acetylpyruvoylglucosamine reduc... 2 359 0.28 - E - - 0 4/4 0 10 2
PA3117 asd aspartate semialdehyde dehydrogenase 1 903 0.31 - E - - 0 3/4 0 52 2
PA4450 murA UDP-N-acetylglucosamine 1-carboxyviny... 3 21 0.34 - P - YES 0 4/4 0 73 1
PA3724 lasB elastase LasB 2 4 0.35 ambiguous N YES - 0 0/4 3 108 4
PA3650 dxr 1-deoxy-d-xylulose 5-phosphate reduct... 3 151 0.36 - E - - 0 4/4 0 77 2
PA5038 aroB 3-dehydroquinate synthase 1 127 0.41 - P - - 0 4/4 0 42 1
PA4411 murC UDP-N-acetylmuramate--alanine ligase 7 932 0.43 - E - - 0 4/4 0 42 5
PA4414 murD UDP-N-acetylmuramoylalanine--D-glutam... 6 931 0.43 - P - - 0 4/4 0 22 1
PA4546 pilS two-component sensor PilS 5 573 0.46 - N YES - 0 2/4 0 18 5
PA5261 algR alginate biosynthesis regulatory prot... 3 624 0.46 - N YES - 0 4/4 0 145 4
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