AEROPATH Target Database

Target Listing

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Page 1 of 3, showing 25 records out of 56 total, starting on record 1, ending on 25
Locus tag Gene name Product name ChEMBL homologs Chemogenomic druggability rank Mean QED Structure-based druggability Essentiality Virulence Factor Drug Target Human homologs Microbes havings orthologs Structures solved Structural homologs XtalPred Class
PA5261 algR alginate biosynthesis regulatory prot... 3 624 0.46 - N YES - 0 4/4 0 145 4
PA4119 aph aminoglycoside 3'-phosphotransferase ... 1 22 0.21 - E - - 0 1/4 0 17 4
PA5038 aroB 3-dehydroquinate synthase 1 127 0.41 - P - - 0 4/4 0 42 1
PA1681 aroC chorismate synthase 1 378 0.52 - E - - 0 4/4 0 27 2
PA3117 asd aspartate semialdehyde dehydrogenase 1 903 0.31 - E - - 0 3/4 0 52 2
PA1456 cheY two-component response regulator CheY 5 329 0.68 - E - - 0 2/4 0 269 1
PA0413 chpA component of chemotactic signal trans... 6 355 0.68 - N YES - 0 2/4 0 357 5
PA4931 dnaB replicative DNA helicase 4 9 0.27 - E - - 0 4/4 0 44 4
PA3640 dnaE DNA polymerase III, alpha chain 4 406 0.49 - E - - 0 4/4 0 9 5
PA1816 dnaQ DNA polymerase III, epsilon chain 3 520 0.54 - E - - 0 4/4 0 8 5
PA3650 dxr 1-deoxy-d-xylulose 5-phosphate reduct... 3 151 0.36 - E - - 0 4/4 0 77 2
PA2191 exoY adenylate cyclase ExoY 1 614 0.57 - N YES - 0 0/4 0 65 3
PA1713 exsA transcriptional regulator ExsA 1 5 0.21 - E YES - 0 1/4 0 1 4
PA3645 fabZ (3R)-hydroxymyristoyl-[acyl carrier p... 1 209 0.53 - E - - 0 4/4 6 120 2
PA0555 fda fructose-1,6-bisphosphate aldolase 6 560 0.17 - E - - 0 3/4 0 71 2
PA1099 fleR two-component response regulator 5 379 0.68 - N YES - 0 0/4 0 311 4
PA1098 fleS two-component sensor 5 866 0.54 - N YES - 0 0/4 0 17 4
PA1455 fliA sigma factor FliA 1 960 0.06 - N YES - 0 2/4 0 31 2
PA4750 folP dihydropteroate synthase 4 61 0.81 - E - YES 0 4/4 0 68 1
PA4407 ftsZ cell division protein FtsZ 5 115 0.57 druggable E - - 0 4/4 3 43 5
PA2586 gacA response regulator GacA 4 752 0.25 - N YES - 0 4/4 0 104 3
PA0928 gacS sensor/response regulator hybrid 11 435 0.67 - N YES - 0 4/4 0 257 5
PA5552 glmU glucosamine-1-phosphate acetyltransfe... 2 276 0.55 - E - - 0 4/4 0 44 2
PA0672 hemO heme oxygenase 1 7 0.54 - E - - 0 2/4 0 5 3
PA3724 lasB elastase LasB 2 4 0.35 ambiguous N YES - 0 0/4 3 108 4
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