AEROPATH Target Database

Target Listing

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Page 1 of 3, showing 25 records out of 56 total, starting on record 1, ending on 25
Locus tag Gene name Product name ChEMBL homologs Chemogenomic druggability rank Mean QED Structure-based druggability Essentiality Virulence Factor Drug Target Human homologs Microbes havings orthologs Structures solved Structural homologs XtalPred Class
PA4406 lpxC UDP-3-O-acyl-N-acetylglucosamine deac... 3 1 0.54 druggable E - - 0 4/4 4 32 1
PA3724 lasB elastase LasB 2 4 0.35 ambiguous N YES - 0 0/4 3 108 4
PA1713 exsA transcriptional regulator ExsA 1 5 0.21 - E YES - 0 1/4 0 1 4
PA0672 hemO heme oxygenase 1 7 0.54 - E - - 0 2/4 0 5 3
PA1430 lasR transcriptional regulator LasR 4 8 0.68 mixed N YES - 0 0/4 23 32 2
PA4931 dnaB replicative DNA helicase 4 9 0.27 - E - - 0 4/4 0 44 4
PA4450 murA UDP-N-acetylglucosamine 1-carboxyviny... 3 21 0.34 - P - YES 0 4/4 0 73 1
PA4119 aph aminoglycoside 3'-phosphotransferase ... 1 22 0.21 - E - - 0 1/4 0 17 4
PA4867 ureB urease beta subunit 2 51 0.70 - E - - 0 3/4 0 48 4
PA4750 folP dihydropteroate synthase 4 61 0.81 - E - YES 0 4/4 0 68 1
PA1882 - probable transporter 2 99 0.54 - E - - 0 2/4 0 16 5
PA4407 ftsZ cell division protein FtsZ 5 115 0.57 druggable E - - 0 4/4 3 43 5
PA5038 aroB 3-dehydroquinate synthase 1 127 0.41 - P - - 0 4/4 0 42 1
PA4415 mraY phospho-N-acetylmuramoyl-pentapeptide... 4 137 0.20 - E - - 0 4/4 0 0 5
PA0576 rpoD sigma factor RpoD 1 147 0.06 - E - - 0 4/4 0 51 5
PA3650 dxr 1-deoxy-d-xylulose 5-phosphate reduct... 3 151 0.36 - E - - 0 4/4 0 77 2
PA4662 murI glutamate racemase 6 208 0.77 - E - - 0 3/4 0 47 1
PA3645 fabZ (3R)-hydroxymyristoyl-[acyl carrier p... 1 209 0.53 - E - - 0 4/4 6 120 2
PA4457 - arabinose-5-phosphate isomerase KdsD 2 238 0.22 - E - - 0 4/4 0 22 1
PA2943 - phospho-2-dehydro-3-deoxyheptonate al... 3 260 0.13 - P - - 0 1/4 0 71 3
PA5552 glmU glucosamine-1-phosphate acetyltransfe... 2 276 0.55 - E - - 0 4/4 0 44 2
PA3477 rhlR transcriptional regulator RhlR 5 300 0.68 - N YES - 0 2/4 0 41 4
PA1456 cheY two-component response regulator CheY 5 329 0.68 - E - - 0 2/4 0 269 1
PA1903 phzE2 phenazine biosynthesis protein PhzE 2 348 0.75 - N YES - 0 0/4 0 46 4
PA4214 phzE1 phenazine biosynthesis protein PhzE 2 349 0.75 - N YES - 0 0/4 0 46 4
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