AEROPATH Target Database

Target Listing

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Page 1 of 3, showing 25 records out of 56 total, starting on record 1, ending on 25
Locus tag Gene name Product name ChEMBL homologs Chemogenomic druggability rank Mean QED Structure-based druggability Essentiality Virulence Factor Drug Target Human homologs Microbes havings orthologs Structures solved Structural homologs XtalPred Class
PA0408 pilG twitching motility protein PilG 5 470 0.68 - E YES - 0 2/4 0 282 1
PA0409 pilH twitching motility protein PilH 5 353 0.68 - N YES - 0 2/4 0 309 1
PA1456 cheY two-component response regulator CheY 5 329 0.68 - E - - 0 2/4 0 269 1
PA4406 lpxC UDP-3-O-acyl-N-acetylglucosamine deac... 3 1 0.54 druggable E - - 0 4/4 4 32 1
PA2192 - conserved hypothetical protein 1 904 0.22 - E - - 0 0/4 0 31 1
PA4414 murD UDP-N-acetylmuramoylalanine--D-glutam... 6 931 0.43 - P - - 0 4/4 0 22 1
PA4450 murA UDP-N-acetylglucosamine 1-carboxyviny... 3 21 0.34 - P - YES 0 4/4 0 73 1
PA4662 murI glutamate racemase 6 208 0.77 - E - - 0 3/4 0 47 1
PA4776 pmrA PmrA: two-component regulator system ... 2 642 0.25 - E - - 0 3/4 0 278 1
PA5038 aroB 3-dehydroquinate synthase 1 127 0.41 - P - - 0 4/4 0 42 1
PA4750 folP dihydropteroate synthase 4 61 0.81 - E - YES 0 4/4 0 68 1
PA4457 - arabinose-5-phosphate isomerase KdsD 2 238 0.22 - E - - 0 4/4 0 22 1
PA4416 murF UDP-N-acetylmuramoylalanyl-D-glutamyl... 6 543 0.58 - E - - 0 4/4 0 7 1
PA0555 fda fructose-1,6-bisphosphate aldolase 6 560 0.17 - E - - 0 3/4 0 71 2
PA1681 aroC chorismate synthase 1 378 0.52 - E - - 0 4/4 0 27 2
PA1455 fliA sigma factor FliA 1 960 0.06 - N YES - 0 2/4 0 31 2
PA3117 asd aspartate semialdehyde dehydrogenase 1 903 0.31 - E - - 0 3/4 0 52 2
PA2977 murB UDP-N-acetylpyruvoylglucosamine reduc... 2 359 0.28 - E - - 0 4/4 0 10 2
PA5552 glmU glucosamine-1-phosphate acetyltransfe... 2 276 0.55 - E - - 0 4/4 0 44 2
PA4417 murE UDP-N-acetylmuramoylalanyl-D-glutamat... 6 525 0.58 - E - - 0 4/4 0 16 2
PA4231 pchA salicylate biosynthesis isochorismate... 2 417 0.75 - N YES - 0 4/4 0 40 2
PA3650 dxr 1-deoxy-d-xylulose 5-phosphate reduct... 3 151 0.36 - E - - 0 4/4 0 77 2
PA3645 fabZ (3R)-hydroxymyristoyl-[acyl carrier p... 1 209 0.53 - E - - 0 4/4 6 120 2
PA1430 lasR transcriptional regulator LasR 4 8 0.68 mixed N YES - 0 0/4 23 32 2
PA0672 hemO heme oxygenase 1 7 0.54 - E - - 0 2/4 0 5 3
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