AEROPATH Target Database

Target Listing

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Page 1 of 12, showing 25 records out of 281 total, starting on record 1, ending on 25
Locus tag Gene name Product name ChEMBL homologs Chemogenomic druggability rank Mean QED Structure-based druggability Essentiality Virulence Factor Drug Target Human homologs Microbes havings orthologs Structures solved Structural homologs XtalPred Class
PA0478 - probable N-acetyltransferase 3 585 0.25 - N - - 3 2/4 2 36 3
PA3702 wspR probable two-component response regul... 2 728 0.25 non-druggable N - - 0 3/4 4 104 4
PA1195 - hypothetical protein 4 770 0.26 non-druggable N - - 2 0/4 5 25 3
PA4006 nadD nicotinic acid mononucleotide adenyly... 1 725 0.26 mixed N - - 0 3/4 7 57 2
PA4190 pqsL probable FAD-dependent monooxygenase 3 962 0.26 - N - - 2 0/4 1 24 1
PA3859 - carboxylesterase 2 592 0.26 druggable N - - 3 1/4 6 13 4
PA3116 - probable aspartate-semialdehyde dehyd... 1 946 0.31 - N - - 0 3/4 1 22 4
PA0019 def polypeptide deformylase 6 3 0.35 mixed E - - 1 4/4 7 170 3
PA5172 arcB ornithine carbamoyltransferase, catab... 3 510 0.35 - N - - 2 3/4 13 239 2
PA3724 lasB elastase LasB 2 4 0.35 ambiguous N YES - 0 0/4 3 108 4
PA4110 ampC beta-lactamase precursor 19 2 0.37 ambiguous N - YES 0 3/4 4 196 4
PA1024 - 2-Nitropropane Dioxygenase 1 696 0.38 druggable N - - 0 2/4 2 11 1
PA5243 hemB delta-aminolevulinic acid dehydratase 1 350 0.40 non-druggable E - - 1 4/4 31 72 2
PA5302 dadX catabolic alanine racemase 2 271 0.40 ambiguous N - YES 0 3/4 1 81 1
PA0288 gpuA 3-guanidinopropionase 2 878 0.41 - N - - 3 2/4 8 262 2
PA1421 gbuA guanidinobutyrase 2 933 0.41 - N - - 3 2/4 6 258 3
PA4959 fimX FimX 1 879 0.46 - N - - 0 1/4 6 26 5
PA5453 gmd GDP-mannose 4,6-dehydratase 1 924 0.46 - N - - 4 1/4 4 119 1
PA2393 - probable dipeptidase precursor 2 838 0.51 - N YES - 4 2/4 1 27 5
PA5396 - hypothetical protein 2 856 0.51 - N - - 3 2/4 2 27 1
PA1010 dapA dihydrodipicolinate synthase 6 142 0.52 - E - - 2 4/4 2 320 1
PA3645 fabZ (3R)-hydroxymyristoyl-[acyl carrier p... 1 209 0.53 - E - - 0 4/4 6 120 2
PA2687 pfeS two-component sensor PfeS 3 694 0.54 - N - - 0 0/4 1 30 5
PA4406 lpxC UDP-3-O-acyl-N-acetylglucosamine deac... 3 1 0.54 druggable E - - 0 4/4 4 32 1
PA4827 - arylamine N-acetyltransferase 6 825 0.54 - N - - 2 2/4 1 34 2
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