AEROPATH Target Database

Target Listing

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Page 1 of 12, showing 25 records out of 281 total, starting on record 1, ending on 25
Locus tag Gene name Product name ChEMBL homologs Chemogenomic druggability rank Mean QED Structure-based druggability Essentiality Virulence Factor Drug Target Human homologs Microbes havings orthologs Structures solved Structural homologs XtalPred Class
PA4406 lpxC UDP-3-O-acyl-N-acetylglucosamine deac... 3 1 0.54 druggable E - - 0 4/4 4 32 1
PA4110 ampC beta-lactamase precursor 19 2 0.37 ambiguous N - YES 0 3/4 4 196 4
PA0019 def polypeptide deformylase 6 3 0.35 mixed E - - 1 4/4 7 170 3
PA3724 lasB elastase LasB 2 4 0.35 ambiguous N YES - 0 0/4 3 108 4
PA1430 lasR transcriptional regulator LasR 4 8 0.68 mixed N YES - 0 0/4 23 32 2
PA0247 pobA p-hydroxybenzoate hydroxylase 1 20 0.87 ambiguous N - - 0 3/4 19 36 1
PA0183 atsA arylsulfatase 6 23 0.58 - N - - 13 1/4 2 21 4
PA4907 - probable short-chain dehydrogenase 15 63 0.82 - N - - 39 4/4 4 685 2
PA3387 rhlG beta-ketoacyl reductase 22 81 0.82 - N - - 41 0/4 2 1119 1
PA4407 ftsZ cell division protein FtsZ 5 115 0.57 druggable E - - 0 4/4 3 43 5
PA3333 fabH2 3-oxoacyl-[acyl-carrier-protein] synt... 6 125 0.73 - N - - 0 2/4 2 78 2
PA0999 pqsD 3-oxoacyl-[acyl-carrier-protein] synt... 6 134 0.71 ambiguous N - - 0 1/4 6 78 1
PA1010 dapA dihydrodipicolinate synthase 6 142 0.52 - E - - 2 4/4 2 320 1
PA3247 - hypothetical protein 4 153 0.68 - N - - 1 0/4 12 42 2
PA5373 betB betaine aldehyde dehydrogenase 13 163 0.66 - N - - 19 4/4 20 553 1
PA5427 adhA alcohol dehydrogenase 22 168 0.81 - N - - 13 2/4 8 382 1
PA3507 - probable short-chain dehydrogenase 7 183 0.77 - N - - 27 1/4 6 870 2
PA0785 azoR1 FMN-dependent NADH-azoreductase 1, AzoR1 1 201 0.69 mixed N - - 1 0/4 8 82 3
PA3645 fabZ (3R)-hydroxymyristoyl-[acyl carrier p... 1 209 0.53 - E - - 0 4/4 6 120 2
PA5302 dadX catabolic alanine racemase 2 271 0.40 ambiguous N - YES 0 3/4 1 81 1
PA3004 - 5'-methylthioinosine phosphorylase 7 310 0.62 - N - - 2 1/4 6 197 2
PA0480 - probable hydrolase 3 324 0.70 - N - - 4 2/4 2 103 1
PA5243 hemB delta-aminolevulinic acid dehydratase 1 350 0.40 non-druggable E - - 1 4/4 31 72 2
PA0148 - probable adenosine deaminase 4 410 0.69 - N - - 3 3/4 8 65 3
PA0223 - probable dihydrodipicolinate synthetase 6 431 0.58 - N - - 2 0/4 4 320 1
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