AEROPATH Target Database
Target Listing
Filter targets
Target Search
Locus Tag (e.g. PA3724)
Gene Name (e.g. lasB)
Product name (e.g. elastase)
Is perturbative (i.e. is essential or virulence factor)
All
Yes
No
Chemogenomic Druggability prediction
All
Yes
No
Structure-based Druggability prediction
All
Yes
No
Human homologs
All
Yes
No
Structure solved
All
Yes
No
PDB homologs
All
Yes
No
Bacterial drug target
All
Yes
No
Filter
Reset
Page 1 of 228, showing 25 records out of 5677 total, starting on record 1, ending on 25
Locus tag
Gene name
Product name
ChEMBL homologs
Chemogenomic druggability rank
Mean QED
Structure-based druggability
Essentiality
Virulence Factor
Drug Target
Human homologs
Microbes havings orthologs
Structures solved
Structural homologs
XtalPred Class
PA0001
dnaA
chromosomal replication initiator pro...
0
-
-
-
E
-
-
0
4/4
0
25
5
PA0002
dnaN
DNA polymerase III, beta chain
0
-
-
-
E
-
-
0
4/4
0
42
2
PA0003
recF
RecF protein
0
-
-
-
N
-
-
0
4/4
0
1
4
PA0004
gyrB
DNA gyrase subunit B
28
53
0.65
-
N
-
YES
2
4/4
0
103
5
PA0005
lptA
lysophosphatidic acid acyltransferase...
3
613
0.62
-
N
YES
-
2
1/4
0
0
5
PA0006
-
conserved hypothetical protein
0
-
-
-
E
-
-
0
2/4
0
27
2
PA0007
-
hypothetical protein
0
-
-
-
N
-
-
0
0/4
0
0
4
PA0008
glyS
glycyl-tRNA synthetase beta chain
0
-
-
-
E
-
-
0
4/4
0
0
5
PA0009
glyQ
glycyl-tRNA synthetase alpha chain
0
-
-
-
E
-
-
0
4/4
0
8
3
PA0010
tag
DNA-3-methyladenine glycosidase I
0
-
-
-
N
-
-
0
4/4
0
7
1
PA0011
-
probable 2-OH-lauroyltransferase
0
-
-
-
N
-
-
0
2/4
0
0
3
PA0012
-
hypothetical protein
0
-
-
-
N
-
-
0
0/4
0
0
1
PA0013
-
conserved hypothetical protein
0
-
-
-
P
-
-
0
3/4
0
0
5
PA0014
-
hypothetical protein
0
-
-
-
N
-
-
0
0/4
0
0
4
PA0015
-
hypothetical protein
0
-
-
-
N
-
-
0
1/4
0
1
3
PA0016
trkA
potassium uptake protein TrkA
0
-
-
-
N
-
-
0
2/4
0
21
2
PA0017
-
conserved hypothetical protein
0
-
-
-
N
-
-
6
4/4
0
19
2
PA0018
fmt
methionyl-tRNA formyltransferase
1
940
0.26
-
E
-
-
4
4/4
0
86
1
PA0019
def
polypeptide deformylase
6
3
0.35
mixed
E
-
-
1
4/4
7
170
3
PA0020
-
hypothetical protein
0
-
-
-
N
-
-
0
2/4
0
0
4
PA0021
-
conserved hypothetical protein
0
-
-
-
N
-
-
0
4/4
0
1
3
PA0022
-
conserved hypothetical protein
0
-
-
-
E
-
-
1
4/4
0
7
1
PA0023
qor
quinone oxidoreductase
10
257
0.58
-
N
-
-
11
2/4
0
213
1
PA0024
hemF
coproporphyrinogen III oxidase, aerobic
1
-
-
-
E
-
-
1
4/4
0
24
3
PA0025
aroE
shikimate dehydrogenase
0
-
-
-
N
-
-
0
4/4
0
89
1
<< previous
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
next >>